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Sumeet Subherwal, MD
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Sumeet Subherwal, MD

Dr. Sumeet Subherwal joined Raleigh Cardiology in October 2013.  He has a special interest in caring for patients with advanced vascular disease including peripheral artery disease (PAD), critical limb ischemia/limb salvage, coronary intervention, venous disease, hypertension, and believes in optimal cardiovascular prevention among this high risk population.

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Dr. Subherwal earned his medical degree from University of California (UC) Irvine School of Medicine in Irvine, CA. He subsequently completed his Masters of Business Adminstration (MBA) from the UC Irvine Paul Merage School of Business. He then completed his residency in internal medicine at Barnes-Jewish Hospital/Washington University in St. Louis, MO, and was a clinical research scholar within the cardiovascular division at Washington University in St. Louis, MO. Dr. Subherwal completed fellowships in cardiovascular disease and interventional cardiovascular disease at Duke University Medical Center. He spent two years in an advanced clinical research fellowship at the  Duke Clinical Research Institute in Durham, NC participating in outcomes and clinical trial research.

He is a member of the American College of Cardiology and the American Venous Forum.  He has a passion for research, especially in PAD, critical limb ischemia, acute coronary syndrome (ACS), bleeding in ACS, clinical trial endpoints and methodology, and venous ablation. He has numerous publications in the field of PAD and ACS in the most prominent cardiovascular journals.


1. Subherwal S, Kobashigawa JA, Cogert G, Patel J, Espejo M, Oeser B. Incidence of acute cellular rejection and non-cellular rejection in cardiac transplantation. Transplant Proc 2004;36:3171-2.

2.Kobashigawa JA, Patel J, Furukawa H, Moriguchi JD, Yeatman L, Takemoto S, Marquez A, Shaw J, Oeser BT, Subherwal S, Wu GW, Kawano J, Laks H. Five-year results of a randomized, single-center study of tacrolimus vs microemulsion cyclosporine in heart transplant patients. J Heart Lung Transplant 2006;25:434-9.

3. Lenzini PA, Grice GR, Milligan PE, Dowd MB, Subherwal S, Deych E, Eby CS, King CR, Porche-Sorbet RM, Murphy CV, Marchand R, Millican EA, Barrack RL, Clohisy JC, Kronquist K, Gatchel SK, Gage BF. Laboratory and clinical outcomes of pharmacogenetic vs. clinical protocols for warfarin initiation in orthopedic patients. J Thromb Haemost 2008;6:1655-62.

4. Subherwal S, Bach RG, Chen AY, Gage BF, Rao SV, Newby LK, Wang TY, Gibler WB, Ohman EM, Roe MT, Pollack CV Jr, Peterson ED, Alexander KP. Baseline risk of major bleeding in non-ST-segment-elevation myocardial infarction: the CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA Guidelines) Bleeding Score. Circulation 2009;119:1873-82.

5. Subherwal S, Rao SV. The economic benefits of the transradial approach. Cardiac Interventions Today 2009;September.

6. Subherwal S, de las Fuentes L, Waggoner AD, Heuerman S, Spence KE, Davila-Roman VG. Central aortic pressure is independently associated with diastolic function. Am Heart J 2010;159:1081-8.

7. Subherwal S, Peterson ED, Chen AY, Roe MT, Washam JB, Gage BF, Bach RG, Bhat DL, Wiviott SD, Lopes RD, Alexander KP, Wang TY. Admission International Normalized Ratio Levels, Early Treatment Strategies, and Major Bleeding Risk Among Non-ST Elevation Myocardial Infarction Patients on Home Warfarin TherapyÑInsights from the NCDR¨. Circulation. 2012 Feb 8.

8. Lopes RD, Subherwal S, Holmes DN, Thomas L, Wang TY, Rao SV, Ohman EM, Roe MT, Peterson ED, Alexander KP. The Association of In-hospital Major Bleeding with Short-, Intermediate-, and Long-term Mortality Among Older Patients with Non-ST Segment Myocardial Infarction. Eur H Jour. 2012 Mar 5.

9. Subherwal S, Peterson ED, Dai D, Thomas T, Messenger JC, Marso SP, Klein LW, Senter S, Feldman DN, Roe MT, Rao SV. Temporal Trends in and Factors Associated with Bleeding Complications Among Patients Undergoing Percutaneous Coronary Intervention: A Report from the National Cardiovascular Data CathPCI Registry. J Am Coll Cardiol. 2012 May 22;59(21):1861-9.

10. Rao SV, Dai D, Subherwal S, Weintraub WS, Brindis RS, Messenger JC, Lopes RD, Peterson ED.

Association Between Peri-procedural Bleeding and Long-term Outcomes Following Percutaneous Coronary Intervention in Older Patients. JACC Cardiovasc Interv. 2012 Sep;5(9):958-65.

11. Subherwal S, Li S, Bhatt DL, Li S, Thomas L, Patel MR Wang TY, Alexander KP, Ohman EM, Gibler WB, Peterson ED, Roe MT. Impact of polyvascular Disease on long-term mortality in older patients with Non-ST-segment myocardial infarction. Circ Cardiovasc Qual Outcomes. 2012 Jun 19.

12. Subherwal S, Anstrom, KJ, Jones WS, Felker MG, Misra S, Conte MS, Hiatt WR, Patel MR. Use of Alternative Methodologies For Evaluation of Composite End Points in Trials of Therapies For Critical Limb Ischemia. Am Heart J. 2012 Sep;164(3):277-84

13. Subherwal S, Patel MR, Kober L, Jones WS, Gislason GH, Berger JS, Torp-Pedersen C, Fosbol EF. Missed Opportunities: The Continued Underutilization of Cardioprotective Medications Among Patients with Lower Extremity Peripheral Arterial Disease. Circulation. 2012 Sep 11;126(11):1345-54.

14. Jones WS, Patel MR, Dai D, Subherwal S, Stafford J, Calhoun S, Peterson ED. Temporal trends and geographic variation of lower-extremity amputation in patients with peripheral artery disease: results from u.s. Medicare 2000-2008. J Am Coll Cardiol. 2012 Nov 20;60(21):2230-6

15. Baklanov DV, Kaltenbach LA, Marso SP, Subherwal S, Feldman DN, Garratt KN, Curtis JP, Messenger JC, Rao SV. The Prevalence and Outcomes of Transradial Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction: Analysis from the NCDR (2007 to 2011).

J Am Coll Cardiol. 2013 Jan 29;61(4):420-6

16. Rao SV, Dai D, Subherwal S, Weintraub WS, Brindis RS, Messenger JC, Lopes RD, Peterson ED.

Association between periprocedural bleeding and long-term outcomes following percutaneous coronary intervention in older patients. JACC Cardiovasc Interv. 2012 Sep;5(9):958-65

17. Daugherty S, Thompson L, Kim S, Rao SV, Subherwal S, Tsai T, Messenger J, Masoudi F. Patterns of Use and Comparative Effectiveness of Bleeding Avoidance Strategies in Men and Women Following Percutaneous Coronary Interventions: An Observational Study from the National Cardiovascular Data Registry J Am Coll Cardiol. 2013 Mar 20

18. Subherwal S, Ohman EM, Mahaffey KW, Rao SV, Alexander JH, Wang TY, Alexander KP, Hasselblad V, Roe MT. Incorporation of bleeding as an element of the composite end point in clinical trials of antithrombotic therapies in patients with non-ST-segment elevation acute coronary syndrome: Validity, pitfalls, and future approaches. Am Heart J. 2013 May;165(5):644-654

19. Jones WS, Patel MR, Dai D, Vemulapalli S, Subherwal S, Stafford J, Peterson ED. High mortality risks after major lower extremity amputation in Medicare patients with peripheral artery disease. Am Heart J. 2013 May;165(5):809-815

20. Subherwal S, Patel M, Tan F, Smolderen K, Jones WS, Tsai T, Ting H, Bhatt D, Spertus J, Chan P. Socioeconomic Disparities in Use of Cardioprotective Medication Among Patients with Peripheral Artery Disease-An Analysis of the American College of Cardiology's NCDR PINNACLE Registry¨ . J Am Coll Cardiol. 2013 May 2

21. Jones WS, Schmit KM, Vemulapalli S, Subherwal S, Patel MR, Hasselblad V, Heidenfelder BL, Chobot MM, Posey R, Wing L, Sanders GD, Dolor RJ. Treatment Strategies for Patients With Peripheral Artery Disease. Comparative Effectiveness Review No. 118. (Prepared by the Duke Evidence-based Practice Center under Contract No. 290-2007-10066-I.) AHRQ Publication No. 13-EHC090-EF. Rockville, MD: Agency for Healthcare Research and Quality; May 2013

22. Jones WS, Patel MR, Dai D, Vemulapalli S, Subherwal S, Stafford J, Peterson ED. High mortality risks after major lower extremity amputation in Medicare patients with peripheral artery disease. Am Heart J. 2013 May;165(5):809-15

23. Baklanov DV, Kim S, Marso SP, Subherwal S, Rao SV.Comparison of bivalirudin and radial access across a spectrum of preprocedural risk of bleeding in percutaneous coronary intervention: analysis from the national cardiovascular data registry. Circ Cardiovasc Interv. 2013 Aug;6(4):347-53



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